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. 2021 Sep 6;20:173. doi: 10.1186/s12934-021-01658-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Upset diagram to show significantly differentially expressed genes in Levilactobacillus brevis Lbr-6108 and Lbr-35 throughout the experiments. Individual lines are denoted by having MRS only (−MSG) or MRS + MSG (+ MSG) followed by the timepoint number. The top graphs compare the number of significantly expressed genes at the same timepoints but with different media (MRS and MRS + MSG) for (A) Lbr-6108 and (B) Lbr-35. The middle graphs compare the T6 (pre-log phase) to T12 (mid-log), T18 (pre-stationary) and T24 (stationary) in only MRS for (C) Lbr-6108 and (D) Lbr-35. The bottom graph compares the T6 (pre-log phase) to T12 (mid-log), T18 (pre-stationary) and T24 (stationary) in MRS + MSG for (E) Lbr-6108 and (F) Lbr-35