TABLE 1.
Demographic, sleep, clinical characteristics, and Psychological impact in the patients with narcolepsy type 1 and controls
Variable | Patients with NT1 (n = 52) | Controls (n = 50) |
---|---|---|
Demographic data | ||
Male/female, n | 14/36 | 21/31 |
Age, years, mean±(SD) | 33.56 ± (11.59) | 34.42 ± (15.11) |
Education, years, mean±(SD) | 13.50 ± (3.31) | 14.42 ± (3.31) |
Age at diagnosis, years, mean (SD) | 17.06 ± (10.29) | |
Disease duration, years, mean (SD) | 17.90 ± (10.62) | |
Medication used, n | ||
Stimulants | 14 | |
Sodium oxybate | 19 | |
Antidepressant | 9 | |
Stimulants plus sodium oxybate | 19 | |
Sleepiness, sleep quality and clinical characteristics | ||
ESS, mean (SD) Pre During P |
_ 11.28 ± (4.53) 9.85 ± (4.50) 0.04* |
_ 5.29 ± (2.79) 5.31 ± (3.04) 0.96 |
PSQI, mean (SD) Pre During P |
_ 4.26 (2.25) 5.34 ± (2.88) 0.01* |
|
SP‐H (NSS), mean (SD) Pre During p |
_ 4.17 ± (4.32) 4.23 ± (4.54) 0.90 |
|
EDS‐NS (NSS), mean (SD) Pre During p |
_ 13.25 ± (5.87) 10.79 ± (5.46) 0.00* |
|
CATA (NSS), mean (SD) Pre During P |
_ 5.38 ± (3.94) 5.10 ± (3.81) 0.55 |
|
NSS, mean (SD) Pre During P |
_ 22.81 ± (11.12) 20.12 ± (10.26) 0.01* |
|
Psychological impact IES‐R, mean (SD) | ||
Total score | 5.87 ± (1.91) | 6.29 ± (1.99) |
Intrusion | 1.83 ± (0.66) | 1.95 ± (0.74) |
Avoidance | 2.00 ± (0.67) | 2.14 ± (0.68) |
Hyperarousal | 2.05 ± (0.82) | 2.20 ± (0.78) |
CATA, cataplexy; EDS‐NS, excessive daytime sleepiness and night‐time sleep; ESS, Epworth Sleepiness Scale; NSS, Narcolepsy Severity Scale total score; NT1, narcolepsy type 1; PSQI, Pittsburgh Sleep Quality Index; SP‐H, Sleep paralysis and hypnagogic hallucinations.
*p < 0.05