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. 2021 Jun 28;8(17):2101222. doi: 10.1002/advs.202101222

Figure 4.

Figure 4

CMA alters the global metabolism of the patients. A) The plasma level of individual metabolic activators including serine, carnitine, nicotinamide riboside, and cysteine as well as B) their association with the 10 most significantly correlated plasma metabolites are presented using the plasma samples obtained from 93 patients in Phase 2 clinical trial. Asterisks indicate statistical significance based on Spearman correlation analysis. FDR value <0.01.