Figure 10. Neutralization of SARS‐CoV‐2 B.1.351 by VHH antibodies.

• A, B
  Neutralization of SARS‐CoV‐2 B.1.351/Beta by the indicated VHH antibody constructs. The neutralization experiment was performed as described in Fig 3A, with the difference being that a mutant‐optimized anti‐RBD/S1 VHH cocktail was used for immunofluorescence staining (see Appendix Fig S13). Two titrations for the Re9F06 trimer are shown, corresponding to the standard (upper row) or a fivefold higher virus inoculum (lower row) that was used for even more stringent neutralization conditions.