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. 2021 Sep 3;9:e11946. doi: 10.7717/peerj.11946

Figure 3. Gene set enrichment analyzes between subtypes by gender and subtypes by lncRNAs.

Figure 3

(A) Cytoscape map showing the upregulated and downregulated biological pathway in 18 male patients compared to matched 18 female GIST patients. (B–D) GSEA maps showing main upregulated pathway in male patients. (E–G) GSEA maps showing main upregulated pathway in female patients. (H) Cytoscape map showing the upregulated biological pathway in the subtype G3/4 GIST patients (tumor size > 5 cm) compared to G1/2 GIST patients (tumor size < 5 cm). (I–K) GSEA map showing the main upregulated pathway in G1/2 patients. (L–N) GSEA map showing the main upregulated pathway in G3/4 patients. Orange nodes mean upregulated gene sets, blue nodes mean downregulated gene sets, node size is proportional to the total number of genes within each gene set.