Table 1.

PICRUSt analysis of predictive metagenomics function of the fecal microbiota.

Description	CON	Obese	P-value
Translation, ribosomal structure, and biogenesis	4084414 ± 153262	3997426 ± 153313	0.70
RNA processing and modification	154 ± 22	389 ± 81	0.02
Transcription	2904158 ± 177021	3129631 ± 140965	0.34
Replication, recombination, and repair	2649832 ± 109236	2617864 ± 106529	0.84
Chromatin structure and dynamics	794 ± 111	998 ± 130	0.26
Cell cycle control, cell division, chromosome partitioning	602493 ± 26095	585050 ± 26259	0.65
Defense mechanisms	1096506 ± 55118	1120853 ± 44694	0.74
Signal transduction mechanisms	1643514 ± 64697	1664604 ± 63506	0.82
Cell wall/membrane/envelope biogenesis	3157429 ± 96701	2793209 ± 109657	0.03
Cell motility	437506 ± 31128	512648 ± 16134	0.06
Cytoskeleton	672 ± 146	967 ± 66	0.10
Extracellular structures	7 ± 3	5 ± 3	0.60
Intracellular trafficking, secretion, and vesicular transport	562194 ± 18826	554831 ± 20164	0.79
Posttranslational modification, protein turnover, chaperones	1524499 ± 49713	1432079 ± 49258	0.22
Energy production and conversion	2567778 ± 60845	2322549 ± 114626	0.09
Carbohydrate transport and metabolism	3128111 ± 70640	2698067 ± 79519	0.00
Amino acid transport and metabolism	4248646 ± 60952	3751842 ± 140894	0.01
Nucleotide transport and metabolism	1711731 ± 62403	1629905 ± 63121	0.38
Coenzyme transport and metabolism	1678606 ± 75618	1629827 ± 73324	0.65
Lipid transport and metabolism	1066536 ± 42025	1065261 ± 36048	0.98
Inorganic ion transport and metabolism	2351984 ± 102963	2298300 ± 87792	0.70
Secondary metabolites biosynthesis, transport, and catabolism	206926 ± 9555	190387 ± 8092	0.22
Function unknown	6627472 ± 327201	6695151 ± 247724	0.87