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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Drug Alcohol Depend. 2020 Jul 23;215:108182. doi: 10.1016/j.drugalcdep.2020.108182

Table 3.

Associations Between Cannabis Trajectory Groups, Socioecological Factors and Opioid Misuse in Young Adulthood (age 19–26)

Cannabis Trajectory Opioids Prescription Opioids Heroin
Unadjusted OR (95% CI) Adjusted OR (95% CI) Unadjusted OR (95% CI) Adjusted OR (95% CI) Unadjusted OR (95% CI) Adjusted OR (95% CI)
Non-Users 1.0 1.0 1.0 1.0 1.0 1.0
Young Adult Onset 1.9 (0.8, 4.3) 1.8 (0.8, 4.1) 2.0 (0.9, 4.8) 2.0 (0.8, 4.9) 1.7 (0.3, 8.2) 1.4 (0.3, 7.2)
Adolescent Onset Limited 2.5 (1.4, 4.7) 2.2 (1.2, 4.4) 2.1 (1.1, 4.1) 2.1 (1.0, 4.4) 4.8 (1.8, 12.9) 3.4 (1.2, 10.0)
Adolescent Onset Chronic 9.0 (4.7, 17.0) 7.2 (3.6, 14.4) 8.9 (4.6, 17.4) 8.1 (3.9, 16.8) 7.8 (2.7, 22.5) 4.7 (1.5, 14.8)
Male Sex 1.8 (1.1, 2.9) 1.5 (0.9, 2.6) 1.3 (0.8, 2.2) 1.1 (0.6, 1.9) 5.2 (1.8, 15.2) 4.6 (1.5, 13.9)
Black Race 0.4 (0.2, 0.8) 0.5 (0.2, 0.9) 0.4 (0.2, 0.8) 0.5 (0.2, 0.9) 0.4 (0.2, 1.0) 0.4 (0.2, 1.2)
Free/Reduced Price Lunch 1.1 (0.7, 1.9) 1.0 (0.6, 1.8) 1.2 (0.7, 2.1) 1.1 (0.6, 2.0) 0.8 (0.4, 1.8) 0.8 (0.3, 1.8)
Intervention Group 1.0 (0.6, 1.6) 1.0 (0.6, 1.7) 1.0 (0.6, 1.6) 1.0 (0.6, 1.7) 0.9 (0.4, 2.0) 0.9 (0.4, 2.1)
Violence Exposure 1.3 (0.8, 2.0) 1.0 (0.6, 1.7) 1.2 (0.7, 2.0) 1.1 (0.6, 1.9) 1.5 (0.7, 3.4) 0.8 (0.3, 2.2)
Early Alcohol Use 1.9 (1.1, 3.3) 1.4 (0.7, 2.6) 1.7 (0.9, 3.0) 1.3 (0.6, 2.5) 3.0 (1.0, 8.9) 2.0 (0.6, 6.8)
Early Tobacco Use 1.8 (1.2, 2.9) 1.1 (0.6, 2.0) 1.5 (0.9, 2.4) 0.9 (0.5, 1.6) 2.6 (1.2, 5.6) 1.2 (0.5, 3.2)
Deviant Peer Affiliation 1.1 (0.8, 1.6) 0.9 (0.6, 1.3) 1.0 (0.7, 1.5) 0.8 (0.5, 1.3) 1.7 (1.0, 2.7) 1.3 (0.8, 2.2)
Neighborhood Disorder 1.3 (0.9, 1.8) 1.1 (0.7, 1.6) 1.3 (0.9, 1.9) 1.1 (0.7, 1.7) 1.4 (0.8, 2.5) 1.1 (0.6, 2.0)