Figure 4. Response profiles across neuron groups to 121 odorants in the sensory cone (n = 3–5).
Neuronal responses for all odorant stimuli at 10−2 dilution were calculated by subtracting solvent-alone responses and corrected for background activity. Thereafter, spike units were sorted using a custom-designed SSSort software algorithm (see STAR Methods).
(A) Heatmap of response profile of six neuron groups (A–F) to 121 odorants; the odorants highlighted in bold evoked behavioral responses in An. coluzzii larvae (Table S1). Each odorant is color coded based on its chemical class.
(B) Tuning curves of the sorted six neuron groups (A–F) in response to 121 odorants. The corresponding kurtosis (k) values were calculated for each neuron group. The top three odorants contributing to the peak response are listed.