TABLE 2.
Correlations of MMPs and TIMPS in nasal tissue homogenates with eosinophilic inflammation and nasal disease severity from all the enrolled subjects
| Tissue Eos | ||||||
|---|---|---|---|---|---|---|
| (Number/HPF) | Blood Eos (%) | LMS | ||||
| r value | p value | r value | p value | r value | p value | |
| MMP‐3 | 0.366 | 0.008 | 0.451 | <0.001 | 0.263 | 0.031 |
| MMP‐7 | 0.418 | 0.002 | 0.260 | 0.033 | 0.306 | 0.012 |
| MMP‐8 | 0.117 | 0.413 | 0.049 | 0.696 | 0.400 | 0.001 |
| MMP‐9 | 0.164 | 0.251 | 0.176 | 0.155 | 0.345 | 0.004 |
| TIMP‐1 | −0.006 | 0.964 | −0.006 | −0.962 | −0.344 | 0.004 |
| TIMP‐2 | −0.01 | 0.944 | −0.034 | 0.788 | 0.290 | 0.017 |
Abbreviations: LMS, Lund‐Mackay scoring system; MMP, matrix metalloproteinases; TIMP, tissue inhibitors of metalloproteinase.