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. 2020 Sep 10;82(5):528–533. doi: 10.1055/s-0040-1716678

Table 1. Mean preoperative and postoperative sinonasal outcome test-22 scores for patients who underwent endoscopic endonasal transphenoidal approach for pituitary adenomas with free mucosal graft reconstruction, stratified by total score and domain scores ( n  = 48) .

Preoperative visit
(mean ± SD)
First postoperative visit, ≤4 weeks after surgery
(mean ± SD)
Second postoperative visit, between 8 and 12 weeks after surgery
(mean ± SD)
Total SNOT-22 15.7 ± 19.5 29.6 ± 20.7 ( p  < 0.01) 16.8 ± 17.2 ( p  = 0.67)
SNOT-22 domains
Rhinologic symptoms 2.7 ± 4.7 9.4 ± 6.3 ( p  < 0.01) 4.4 ± 4.7 ( p  = 0.03)
Extra-rhinologic symptoms 1.0 ± 2.2 3.5 ± 3.4 ( p  < 0.01) 1.6 ± 2.3 ( p  = 0.10)
Ear/Facial symptoms 1.6 ± 2.7 4.7 ± 5.2 ( p  < 0.01) 3.4 ± 8.6 ( p  = 0.10)
Psychological dysfunction 6.5 ± 8.5 8.7 ± 7.4 ( p  = 0.05) 6.3 ± 7.6 ( p  = 0.84)
Sleep dysfunction 5.8 ± 6.6 8.9 ± 7.8 ( p  = 0.01) 5.7 ± 6.4 ( p  = 0.96)

Abbreviations: SD, standard deviation; SNOT-22, Sinonasal Outcome Test-22.