Figure 6.

Comparison of the performance of CellCall with CellPhoneDB, CellChat, iTALK and SingleCellSignalR on the scRNA-seq dataset of human testicular cells (from ST cells to SSCs). (A) UpSetR plot of results from the five tools with their own default cut-offs. (B) Comparison of the literature support rates of CellCall and four other tools (Fisher's exact test). (C) The ROC curves of these methods. (D) UpSetR plot of results from the five tools with their own optimal cut-point values (the black dots on the curves, which defined by Youden Index).