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. 2021 Sep 2;14:4399–4407. doi: 10.2147/JIR.S317147

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© 2021 Deng et al.

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Time course of inflammatory factors after stroke onset (days 1 to 7). Significant changes over time were observed in the expression levels of IL-4, IL-6, and IL-10 in patients with END compared with patients without END (P<0.05). IL-4 levels peaked at day 2 and then rapidly decreased at day 3 (A). IL-6 levels were obviously increased from days 1 to 7 after EVT (B). IL-10 (C) levels also peaked at day 2 and then rapidly decreased at day 3. No significant change over time was found in the expression levels of IL-2 (D), TNF-α (E), and INF-γ (F) between patients with END and patients without END (P>0.05). *P<0.05, **P<0.01, ***P<0.001.

Abbreviation: END, early neurological deterioration.