Table 2.
Adjusted and Unadjusted Means of OGTT at one-year follow-up for cases and controls
| Group | Unadjusted Means | Adjusted mean | Adjusted mean difference with 95% CI | ||
|---|---|---|---|---|---|
| Baseline | Follow-up | ||||
| BMI (Kg/m2) | Cases | 21.0 (1.79) | 21.6 (1.65) | 21.5 (0.387) | 0.5 [− 0.6–1.6] |
| Controls | 20.7 (2.94) | 20.9 (2.64) | 21 (0.387) | ||
| FEV1 (% predicted) | Cases | 85.5 (24.3) | 85.2 (23.0) | 85.6 (3.8) | 4.5 [− 7.8–16.8] |
| Controls | 81.9 (20.1) | 81.7 (26.9) | 81.1 (4.5) | ||
| Basal glucose (mg/dL) | Cases | 87.2 (16.2) | 89 (10.4) | 86 (2.7) | 8.7 [0.7–16.7] |
| Controls | 77.2 (12.8) | 74.2 (14.6) | 77.2 (2.7) | ||
| 120 min glucose (mg/dL) | Cases | 123 (49) | 131 (72) | 136 (14) | − 6 [− 48–36] |
| Controls | 135 (59) | 148 (68) | 142 (14) | ||
| Glucose AUC | Cases | 7.54 (1.81) | 7.72 (2.61) | 7.79 (0.44) | − 0.03 [− 1.35–1.29] |
| Controls | 7.67 (1.83) | 7.89 (2.05) | 7.82 (0.46) | ||
| β-cell glucose sensitivity (pmol × min−1 × m−2 × mM−1) | Cases | 69.2 (51.3) | 56.2 (33.0) | 52.7 (6.1) | − 6.1 [− 24.7–12.4] |
| Controls | 55.6 (35.2) | 55 (25.1) | 58.9 (6.4) | ||
| 30 min C-peptide (ng/mL) | Cases | 4.3 (2.2) | 3.7 (1.4) | 3.4 (0.3) | 0.0 [− 0.9–0.9] |
| Controls | 3.2 (1.5) | 3.1 (1.3) | 3.4 (0.3) | ||
| 30 min insulin (µU/mL) | Cases | 40 (30) | 25 (16) | 23 (4) | 4 [− 8–16] |
| Controls | 20 (16) | 17 (10) | 19 (3) | ||
| OGTT insulin clearance (L × min−1 × m−2) | Cases | 1.27 (0.35) | 1.75 (0.69) | 2.13 (0.55) | − 0.14 [− 1.88–1.60] |
| Controls | 1.74 (0.54) | 2.68 (2.73) | 2.27 (0.57) | ||
| 2 h OGIS (ml × min−1 × m−2) | Cases | 439 (56) | 458 (49) | 460 (37) | − 67 [− 170–36] |
| Controls | 527 (74) | 542 (87) | 527 (24) | ||
Standard deviations for unadjusted means and standard errors for adjusted mean