Fig. 3.

Percent drug retained in MDA-MB-231 tumors. Formulations (5 mg/mL each) were administered as 0.05 mL direct injections into MDA-MB-231 tumors implanted on the flanks of female BALB/c mice (n = 4 or 5 per group), and tumor tissues were collected 5 days later. The percent of drug retained was calculated based on the concentration of drug detected (ng/g of tumor) and tumor weight. Group mean docetaxel (blue bars) and paclitaxel percent (red bars) as well as individual tumor percent (symbols) are plotted; error bars = ± 1 SD