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. 2021 Sep 6;11:17733. doi: 10.1038/s41598-021-97148-z

Figure 6.

Figure 6

PS106 reduced aggregate formation in C. elegans strain expressing polyglutamine. (a) Representative DIC and GFP images of C. elegans strain expressing polyglutamine (Q82) (GF66) upon 36 h of treatment with DMSO or 25 µM PS106. (b, c) Percent distribution of the number of polyglutamine aggregates upon treatment with (b) 5 µM PS83 or (c) 25 µM PS106. Three biological replicates with ~ 30 worms/replicate were scored and analyzed. p-values were determined from Chi-square test. NS not significant, *p < 0.05, **p < 0.01.