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Effect of co-administration of oral BD and intraperitoneal leptin in WT mice under high fat diet. (A) Body weight change, (B) epididymal WAT weight, (C) cumulative food intake, (D) plasma β-hydroxybutyrate concentration. Values are means ± SEM (n = 7 for Saline + Water, 6 for Leptin + Water, 6 for Saline + BD, 9 for Leptin + BD). *P < 0.05, **P < 0.01 (Bonferroni's test) (A,C). NS, not significant, *P < 0.05, **P < 0.01 (Student’s t-test) (B,D).
