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. 2021 Aug 24;8:665873. doi: 10.3389/fmed.2021.665873

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Copyright © 2021 Mariottoni, Jiang, Prestwood, Jain, Suwanpradid, Whitley, Coates, Brown, Erdmann, Corcoran, Gregory, Jaleel, Zhang, Harris-Tryon and MacLeod.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Antimicrobial peptides and proteins are transcriptionally upregulated in key cell populations within HS skin lesions. (A) Dot plot showing the percent expressed and average expression of AMPs between key cellular populations in HS skin. (B) Violin plots of AMP expression within key cellular populations in HS and HC skin. AMP, antimicrobial peptides and protein; cDC, conventional dendritic cell; HC, healthy control; KC, keratinocyte; LC, Langerhans cell; M/M, monocyte/macrophage; pDC, plasmacytoid dendritic cell; SG, sweat gland cell; TC, T cell.