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. 2021 Aug 24;9:722917. doi: 10.3389/fcell.2021.722917

FIGURE 2.

FIGURE 2

Immune cell infiltration of primary breast cancer and brain metastasis breast cancer. Immune cell infiltration analysis of primary breast cancer and brain metastasis breast cancer using CIBERSORTx. The primary breast cancer samples range from GSM3587381 to GSM3587396; the others are brain metastasis samples. Raw data are downloaded from the GEO database. Data set: GSE125989, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE125989. The difference between the primary tumor site and brain metastasis tumor is not statistically significant. More subgroups should be analyzed for a better understanding of the brain metastasis immune microenvironment. Furthermore, further discovery on phenotype and personalized expression is needed to illustrate the immune cell profile.