TABLE 1.

The demographical information and paternal and maternal haplogroups of our included 50 Han Chinese individuals.

Ind	Group	Status	MtDNA Haplogroup	Sex	Y-chromosome Haplogroup	Key Y-mutations
N0726	Han_Qiannan	Unrelated Healthy	Z3	Female	NA	NA
N0738	Han_Anshun	Unrelated Healthy	B5a1c1	Female	NA	NA
N0741	Han_Anshun	Unrelated Healthy	B5a1c1	Female	NA	NA
N0743	Han_Anshun	Unrelated Healthy	D5b1c	Male	O2a1c1a1a1a1e1a	[′18404653 Y16154′]
N0745	Han_Anshun	Unrelated Healthy	N9a4	Male	O2a1c1a1a1a1a1a1b	①
N0748	Han_Anshun	Unrelated Healthy	B5a1c1	Male	O2a2a1a2a1a	[′16880955 F2309,′ ′19566267 F3085′]
N0749	Han_Anshun	Unrelated Healthy	F1a′c′f	Male	O1b1a1a1b1a	⑤
N0750	Han_Anshun	Unrelated Healthy	B4	Female	NA	NA
N0751	Han_Anshun	Unrelated Healthy	B5a1c1	Female	NA	NA
N0753	Han_Anshun	Unrelated Healthy	D4a5	Female	NA	NA
N0754	Han_Anshun	Unrelated Healthy	C4a1′5	Female	NA	NA
N0764	Han_Anshun	Unrelated Healthy	F1a1	Female	NA	NA
N0765	Han_Anshun	Unrelated Healthy	M7b1a1	Female	NA	NA
N0775	Han_Anshun	Unrelated Healthy	B5a1c1	Female	NA	NA
N0733	Han_Anshun	Unrelated Healthy	D5a3	Female	NA	NA
N0735	Han_Anshun	Unrelated Healthy	D4j11	Male	O2a1c1a1a1a1e2a	[′15953241 FGC54507′]
N0736	Han_Qiandongnan	Unrelated Healthy	B4a2b	Female	NA	NA
N0740	Han_Qiandongnan	Unrelated Healthy	F1a1d	Female	NA	NA
N0742	Han_Qiandongnan	Unrelated Healthy	M7a1a	Male	O1b1a1a1a1a1a1b	[′2738084 Z24091,′ ′23959373 Z24093′]
N0746	Han_Qiandongnan	Unrelated Healthy	D4b2b	Female	NA	NA
N0747	Han_Qiandongnan	Unrelated Healthy	F1a1	Female	NA	NA
N0752	Han_Qiandongnan	Unrelated Healthy	F4a2	Female	NA	NA
N0761	Han_Qiandongnan	Unrelated Healthy	B5a1c1	Female	NA	NA
N0770	Han_Qiandongnan	Unrelated Healthy	B4h1	Male	O2a1c1a1a1a1a1a1a1a1	[′22548606 F1495,′ ′23976986 F1418′]
N0771	Han_Qiandongnan	Unrelated Healthy	D4a3b2	Female	NA	NA
N0774	Han_Qiandongnan	Unrelated Healthy	D4	Female	NA	NA
N0727	Han_Qiannan	Unrelated Healthy	B4a2b	Male	O2a2b1a2a1a2	①
N0737	Han_Qiannan	Unrelated Healthy	D4e1a2	Male	O1b1a1b1	③
N0739	Han_Qiannan	Unrelated Healthy	D5a2a1	Female	NA	NA
N0744	Han_Qiannan	Unrelated Healthy	M7b1a1	Female	NA	NA
N0728	Han_Qiannan	Unrelated Healthy	M7c3	Male	O2a1c1a1a1a1a1a1b	②
N0755	Han_Qiannan	Unrelated Healthy	M9b	Male	O2b1a	④
N0729	Han_Qiannan	Unrelated Healthy	M9b	Female	NA	NA
N0756	Han_Qiannan	Unrelated Healthy	F1a1	Female	NA	NA
N0757	Han_Qiannan	Unrelated Healthy	C7	Male	O1a1a1b2a1	[′8598326 Z39268,′ ′22908919 SK1571′]
N0758	Han_Qiannan	Unrelated Healthy	B5b2c	Male	O2a2b1a2a1a2	①
N0772	Han_Qiannan	Unrelated Healthy	B5a1c1	Female	NA	NA
N0773	Han_Qiannan	Unrelated Healthy	F1a1	Male	O2a1a1a	[′14928001 F1867′]
N0731	Han_Qiannan	Unrelated Healthy	B4c1a	Male	O2a2b1a2a1a2	①
N0734	Han_Qiannan	Unrelated Healthy	G2a	Male	O2a2b1a1a	[′2800495 F8,′ ′6840710 F42′]
N0759	Han_Qianxinan	Unrelated Healthy	B5a	Male	O2a1c1a1a1a1a1a1b	②
N0760	Han_Qianxinan	Unrelated Healthy	B4a	Female	NA	NA
N0762	Han_Qianxinan	Unrelated Healthy	F1c1a1	Female	NA	NA
N0763	Han_Qianxinan	Unrelated Healthy	B5a1c1	Female	NA	NA
N0730	Han_Qianxinan	Unrelated Healthy	B5a1	Female	NA	NA
N0766	Han_Qianxinan	Unrelated Healthy	F1d1	Female	NA	NA
N0767	Han_Qianxinan	Unrelated Healthy	F1a2a	Female	NA	NA
N0768	Han_Qianxinan	Unrelated Healthy	F1a2a	Female	NA	NA
N0769	Han_Qianxinan	Unrelated Healthy	B4b1a2	Male	D1a1a1a1a2a∼	[′16411247 Z44637′]
N0732	Han_Qianxinan	Unrelated Healthy	M10a1b	Male	O1a1a1a1a1a1b1	[′23159740 CTS11553′]

① [′14173991 F242,′ ′14946079 F273,′ ′19371700 CTS10286,′ ′19436515 CTS10401,′ ′22821767 CTS10888,′ ′23024318 F634′].

② [′6655747 F793,′ ′7316384 Z43869,′ ′8568806 F1316C,′ ′14746939 Z43872,′ ′15912372 F2035,′ ′16253175 F2108,′ ′18241027 Z43875,′ ′18705724 Z43876,′ ′21283525 Z43877′].

③ [′8562287 F1309,′ ′14065037 F1685,′ ′14263051 F1742,′ ′16521659 F2189,′ ′17326573 F2445,′ ′22742290 F3353′].

④ [′14336908 F1770,′ ′16718236 F2244,′ ′16733921 F2247,′ ′22676898 F3338′].

⑤ [′15097700 B426,′ ′15320317 Z23672,′ ′16794293 Y9320,′ ′18816557 FGC29898′].