Table 1.
Clinical and Demographic Characteristics of Analyzed COVID-19 and MERS- CoV Infected Patients’ samples
| Characteristics | Total | COVID-19 Patients | MERS-CoV Patients | ||||
|---|---|---|---|---|---|---|---|
| Healthy Donors | **Asymptomatic Grade A | **Mild Grade B | **Moderate Grade C | **Sever Grade D | Sever ICU-Cases | ||
| Number of Participants (%) | 139 | 10 (7.2%) | 29 (20.86%) | 47 (33.81%) | 24 (17.27%) | 22 (15.83%) | 7 (5.03%) |
| Median Age (Years) | 47 | 38 | 38 | 41 | 58 | 62 | 51 |
| Gender | |||||||
| Female | 58 (41.73%) | 5 | 12 | 21 | 12 | 8 | 0 |
| Male | 81 (58.27%) | 5 | 17 | 26 | 12 | 14 | 7 |
| Underlying Disease | |||||||
| Hypertension | 30 (21.6%) | 0 | 0 | 5 | 13 | 7 | 5 |
| Diabetes Mellitus | 24 (17.3%) | 0 | 1 | 1 | 9 | 8 | 5 |
| Kidney Diseases | 13 (9.4%) | 0 | 2 | 3 | 5 | 3 | 0 |
| Heart Diseases | 7 (5%) | 0 | 2 | 2 | 2 | 1 | 0 |
| Other* | 28 (20.14%) | 0 | 2 | 5 | 8 | 7 | 6 |
| Disease Severity/ICU | 34 (20.4%) | 0 | 1 | 3 | 11 | 12 | 7 |
| Admission: | |||||||
| Alive | 25 | 1 | 3 | 9 | 8 | 4 | |
| Dead | 9 | 0 | 0 | 2 | 4 | 3 | |
| Virus Shedding in Plasma: | |||||||
| Positive | 51 | 0 | 0 | 3 | 3 | NA | |
| Negative | 12 | 16 | 5 | 12 | NA | ||
| Outcome | |||||||
| Deceased | 5 (4.1%) | 0 | 0 | 2 | 3 | 3 | |
| Alive | 118 (96.7%) | 28 | 47 | 22 | 19 | 4 | |
| Number of samples for proteomics analysis: | |||||||
| Deceased | 5 | 0 | 0 | 2 | 3 | 3 | |
| Alive | 38 | 10 | 10 | 6 | 12 | 4 | |
Notes: *Other conditions include; Heart, Lung and Renal Disease and Malignancy. **Asymptomatic; Grade A, are patients with no signs or symptoms of infection; Mild; grade B include Patients with upper respiratory tract infection symptoms and other mild symptoms such as fever and gastrointestinal symptoms without evidence of pneumonia. In KFSHRC guidelines, we have an additional category, which is the Moderate cases: grade C, patients with hypoxia, with oxygen saturation less than 93% at rest or presence of pneumonia. The Severe disease; grade D refers to dyspnea, respiratory rate ≥30/ min, blood oxygen saturation ≤93%, partial pressure of arterial oxygen to fraction of inspired oxygen ratio <300, or lung infiltrates >50% within 24 to 48 hours.