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. 2021 Aug 24;8:724792. doi: 10.3389/fsurg.2021.724792

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Copyright © 2021 Guo, Zhou, Ma, Wang, Ge, Wang, Ji, Wang, Zhang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of genomic instability-related lncRNAs in patients with HCC. (A) Waterfall summarized mutational data from patients with HCC. (B) Mutational frequencies in the top 10 genes in the training and testing cohorts. (C) Differentially expressed lncRNAs between GS group and GU group. (D) Hierarchical cluster analyses of TCGA patients with liver cancer based on the expression pattern of 82 genomic instability-related lncRNAs. (E) Boxplots of somatic mutations in the GU-like and GS-like groups. (F) Boxplots of TP53 expression level in the GU-like and GS-like groups.