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. 2021 Aug;10(8):3402–3414. doi: 10.21037/tau-21-562

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2021 Translational Andrology and Urology. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Bioinformatics analysis of the proteins identified by iTRAQ based proteomics technology. (A) The majority of proteins were co-identified at both postoperative time points, indicating the repeatability of urine samples. (B) Molecular annotation of DEPs from Exp-2. (C) Interaction network with biological significance of DEPs from Exp-2. (D) Involved disease and functions of DEPs from Exp-2. (E) Significantly enriched signaling pathways of DEPs from Exp-2. iTRAQ, isobaric tags for relative and absolute quantitation; DEPs, differentially expressed proteins; Exp-1, the first iTRAQ experiment, the postoperative urine samples were collected within one week after operation; Exp-2, the second iTRAQ experiment, the postoperative urine samples were collected over two weeks after operation.