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. 2021 Aug 24;12:723566. doi: 10.3389/fimmu.2021.723566

Table 1.

Summary of responses to key CRC HLA-I phosphopeptides.

Phosphopeptide RVAsPTSGV VMIGsPKKV RRGsFEVTL
Protein of Origin IRS2 TNS3 SELH
HLA-binding A*02 A*02 C*07
Samples colo205 & hct116 sw620 CRC1, CRCLM1, CRCLM2
Other malignancies Melanoma & Leukemia Melanoma & Leukemia
TIL responses +++ ++
HD PBMC responses ++ +++ +
CRC patient PBMC +++ +++ +++

+ low, ++ moderate, +++ strong responses, - not detected.