Table 1. Patients’ characteristics.
| Demographic and clinicopathologic characteristics of included patients | Xinhua Hospital (N=174) | Chongming Branch Hospital (N=38) |
|---|---|---|
| Female sex | 119 (68.4%) | 29 (76.3%) |
| Age, years (median, range) | 67 [28–91] | 67 [42–90] |
| Differentiation | ||
| Well | 19 (10.9%) | 5 (13.2%) |
| Moderate | 96 (55.2%) | 15 (39.5%) |
| Poor | 59 (33.9%) | 18 (47.4%) |
| T stage, 7th ed AJCC | ||
| Tis | 12 (6.9%) | 3 (7.9%) |
| T1 | 12 (6.9%) | 2 (5.3%) |
| T2 | 51 (29.3%) | 15 (39.5%) |
| T3 | 78 (44.8%) | 16 (42.1%) |
| T4 | 21 (12.1%) | 2 (5.3%) |
| Lymph node | ||
| Positive | 63 (36.2%) | 12 (31.6%) |
| Negative, ≥6 nodes examined | 7 (4.0%) | 5 (13.2%) |
| Negative, <6 nodes examined or data not available | 104 (59.8%) | 21 (55.3%) |
| AJCC stage, 7th ed* | ||
| 0 | 12 (6.9%) | 3 (7.9%) |
| 1 | 12 (6.9%) | 2 (5.3%) |
| 2 | 37 (21.3%) | 15 (39.5%) |
| 3 | 92 (52.9%) | 16 (42.1%) |
| 4A** | 21 (12.1%) | 2 (5.3%) |
| Concomitant cholelithiasis | 109 (62.6%) | 28 (73.7%) |
| TBIL, μmol/L (median, range) | 12.3 (2–373) | 13.0 (7–244) |
| ALT, U/L (median, range) | 28 (5–1110) | 16 (3–191) |
| CA199, U/mL (median, range) | 36.3 (0.6–6375.0, 1 missing) | 32.4 (0.6–474.0) |
| CA125, U/mL (median, range) | 22.8 (1.6–742.5, 1 missing) | 16.6 (0.6–134.0) |
| CEA, ng/mL (median, range) | 3.2 (0.3–285.2, 2 missing) | 6.9 (1.9–18.0) |
| Fibrinogen, g/L (median, range) | 3.96 (1.26–8.56) | 3.56 (2.01–7.20) |
| INR (median, range) | 1.01 (0.78–1.92) | 0.97 (0.68–1.40) |
| R0 resection | 91 (52.3%) | 15 (39.5%) |
| Year of surgery, 2006–2010*** | 85 (38.5%) | 15 (39.5%) |
| No. of events (deaths) | 111 (63.8%) | 25 (65.8%) |
*, T, N, and AJCC stage were measured with reference to the AJCC staging manual, 7th ed; **, patients with stage 4B were inoperable, so were not involved; ***, dichotomization here is only for data presentation. When indicated in the model, year of surgery was regarded as a continuous variable.