Figure 5.

Effect of daidzein on Akt/GSK3β/Nrf2 signaling in Con A-challenged mice. Mice were sacrificed, and liver tissues were harvested 12 h after Con A injection. (A-D) Western blot analysis showing nuclear Nrf2, HO-1, and NQO1 expression in the liver and (E-G) western blot analysis showing p-Akt and p-GSK3β expression in the liver. All the results were obtained from at least three independent experiments. Data are expressed as the mean ± SD (n=4 per group). ***P<0.001 vs. the control group. ^#P<0.05 and ^##P<0.01 vs. the Con A group.