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. 2021 Aug;9(15):1228. doi: 10.21037/atm-21-378

Figure 7.

Figure 7

Mechanism of the protective effect of daidzein in Con A-induced liver injury. Daidzein regulates Nrf2 signaling and Bax and Bcl-2 expression via the PI3K/Akt/GSK-3β pathway, thereby reducing the oxidative stress response and hepatocyte apoptosis, which eventually alleviates liver damage in Con A-induced hepatitis.