Table 1.
Patient Characteristics associated with Post-Hepatectomy Liver Failure after Minor Hepatectomy
| Total, n (%) | PHLF, n (%) | No PHLF, n (%) | P value | |
|---|---|---|---|---|
| Overall | 7029 | 187 (2.7) | 6842 (97.3) | |
| Age, mean (SD) | 59.8 (14.0) | 64.9 (11.2) | 59.7 (14.0) | < 0.001 |
| Sex | ||||
| Male | 3399 (48.4) | 132 (3.9) | 3267 (96.1) | < 0.001 |
| Female | 3630 (51.6) | 55 (1.5) | 3575 (98.5) | |
| BMI, mean (SD) | 28.6 (6.4) | 28.3 (5.8) | 28.6 (6.4) | 0.650 |
| Race/Ethnicity | 0.349 | |||
| Non-Hispanic white | 4383 (62.4) | 107 (2.4) | 4276 (97.6) | |
| Non-Hispanic black | 529 (7.5) | 13 (2.5) | 516 (97.5) | |
| Hispanic | 332 (4.7) | 9 (2.7) | 323 (97.3) | |
| Other/Unknown | 1785 (25.4) | 58 (3.3) | 1727 (96.8) | |
| ASA Class | < 0.001 | |||
| I/II | 1972 (28.1) | 21 (1.1) | 1951 (98.9) | |
| III/IV/V | 5057 (71.9) | 166 (3.3) | 4891 (96.7) | |
| Diabetes | 0.098 | |||
| Yes | 1247 (17.7) | 42 (3.4) | 1205 (96.6) | |
| No | 5782 (82.3) | 145 (2.5) | 5637 (97.5) | |
| Smoking | 0.303 | |||
| Yes | 1079 (15.4) | 34 (3.1) | 1045 (96.9) | |
| No | 5950 (84.7) | 153 (2.6) | 5797 (97.4) | |
| Preoperative ascites, n (%) | < 0.001 | |||
| Yes | 48 (0.7) | 9 (18.8) | 39 (81.3) | |
| No | 6981 (99.3) | 178 (2.6) | 6803 (97.5) | |
| Preoperative sepsis, n (%) | 0.095 | |||
| Yes | 91 (1.3) | 5 (5.5) | 86 (94.5) | |
| No | 6938 (98.7) | 182 (2.6) | 6756 (97.4) | |
| Bleeding disorder, n (%) | < 0.001 | |||
| Yes | 250 (3.6) | 20 (8.0) | 230 (92.0) | |
| No | 6779 (96.4) | 167 (2.5) | 6612 (97.5) | |
| Preoperative transfusion, n (%) | 0.095 | |||
| Yes | 41 (0.6) | 3 (7.3) | 38 (92.7) | |
| No | 6988 (99.4) | 184 (2.6) | 6804 (97.4) | |
| Emergency surgery, n (%) | 0.052 | |||
| Yes | 53 (0.8) | 4 (7.6) | 49 (92.5) | |
| No | 6976 (99.3) | 183 (2.6) | 6793 (97.4) | |
| Bilirubin >1.2 | < 0.001 | |||
| Yes | 421 (6.0) | 26 (6.2) | 395 (93.8) | |
| No | 6608 (94.0) | 161 (2.4) | 6447 (97.6) | |
| SGOT > 40 | < 0.001 | |||
| Yes | 1216 (17.3) | 82 (6.7) | 1134 (93.3) | |
| No | 5813 (82.7) | 105 (1.8) | 5708 (98.2) | |
| INR > 1.5 | 0.148 | |||
| Yes | 187 (2.7) | 4 (5.2) | 73 (94.8) | |
| No | 6842 (97.3) | 183 (2.6) | 6769 (97.4) | |
| Preoperative alkaline phosphatase | 106.1 (80.6) | 134.1 (106.0) | 105.3 (79.7) | < 0.001 |
| Preoperative hematocrit | 39.6 (4.9) | 39.4 (5.9) | 39.6 (4.9) | 0.625 |
| Neoadjuvant Therapy, n (%) | 0.511 | |||
| Yes | 1357 (19.3) | 32 (2.4) | 1325 (97.6) | |
| No/Unknown | 5672 (80.7) | 155 (2.7) | 5517 (97.3) | |
| Viral Hepatitis, n (%) | < 0.001 | |||
| B and/or C | 888 (12.6) | 46 (5.2) | 842 (94.8) | |
| None/Other/Unknown | 6141 (87.4) | 141 (2.3) | 6000 (97.7) | |
| Biliary Stent | 0.024 | |||
| Yes | 248 (3.5) | 13 (5.2) | 235 (94.8) | |
| No | 6781 (96.5) | 174 (2.6) | 6607 (97.4) |
Abbreviations: SD, standard deviation; BMI, body mass index; ASA, American Society of Anesthesiologists Classification; SGOT, aspartate transaminase; INR, international normalized ratio