Table 3.
Multivariable Analysis for All Patients with PHLF
| PHLF n (%) |
Adjusted Odds Ratio (95% CI) |
P value | |
|---|---|---|---|
| Age, mean (SD)* | 64.9 (11.2) | 1.21 (1.05 - 1.38) | 0.008 |
| Sex | |||
| Male | 132 (3.9) | 1.00 (REF) | - |
| Female | 55 (1.5) | 0.62 (0.45 - 0.85) | 0.003 |
| ASA Class | |||
| I/II | 21 (1.1) | 1.00 (REF) | - |
| III/IV/V | 166 (3.3) | 1.85 (1.10 - 3.11) | 0.021 |
| Ascites | 9 (18.8) | 4.94 (2.45 - 9.94) | < 0.001 |
| Bleeding disorder | 20 (8.0) | 2.10 (1.18 - 3.44) | 0.011 |
| Elevated SGOT > 40 | 82 (6.7) | 2.11 (1.53 - 2.92) | < 0.001 |
| Surgical Pathology | |||
| Benign | 19 (1.0) | 1.00 (REF) | - |
| Primary Hepatobiliary | 120 (5.5) | 2.14 (1.29 - 3.54) | 0.003 |
| Secondary/Unknown | 48 (1.7) | 1.09 (0.74 - 1.59) | 0.677 |
| Operative Time (hours), mean (SD)** | 4.4 (2.0) | 1.17 (1.09 - 1.26) | < 0.001 |
| Surgical Approach | |||
| Minimally Invasive | 25 (1.2) | 1.00 (REF) | - |
| Open/Other | 162 (3.3) | 1.98 (1.33 - 2.94) | < 0.001 |
| Liver Texture | |||
| Normal/Not documented | 97 (1.8) | 1.00 (REF) | - |
| Cirrhotic/Congested/Fatty/Fibrotic | 90 (5.3) | 1.92 (1.36 - 2.72) | < 0.001 |
| Pringle Maneuver | 59 (4.6) | 1.60 (0.91 - 2.82) | 0.100 |
| Surgical Drain | 113 (3.9) | 1.57 (0.95 - 2.60) | 0.078 |
*
OR reported for each additional 10 years
**
OR reported for each additional hour
Abbreviations: PHLF, post-hepatectomy liver failure; SD, standard deviation; ASA, American Society of Anesthesiologists Classification; SGOT, aspartate transaminase; MIS, minimally invasive surgery