Table 4.
Multivariable Analysis for Patients with Grade B/C PHLF
| Grade B/C PHLF n (%) |
Adjusted Odds Ratio (95% CI) |
P value | |
|---|---|---|---|
| Age, mean (SD)* | 65.0 (10.5) | 1.19 (0.99 - 1.42) | 0.069 |
| Sex | |||
| Male | 65 (1.9) | 1.00 (REF) | - |
| Female | 35 (1.0) | 0.93 (0.59 - 1.46) | 0.739 |
| ASA Class | |||
| I/II | 10 (0.5) | 1.00 (REF) | - |
| III/IV/V | 90 (1.8) | 1.99 (0.98 - 4.05) | 0.057 |
| Ascites | 6 (12.5) | 4.63 (1.56 - 13.78) | 0.006 |
| Bleeding disorder | 14 (5.6) | 2.62 (1.09 - 6.32) | 0.032 |
| Elevated SGOT > 40 | 50 (4.1) | 2.51 (1.72 - 3.64) | < 0.001 |
| Surgical Pathology | |||
| Benign | 6 (0.3) | 1.00 (REF) | - |
| Primary Hepatobiliary | 70 (3.2) | 4.03 (2.12 - 7.64) | < 0.001 |
| Secondary/Unknown | 24 (0.8) | 1.79 (0.94 - 3.40) | 0.074 |
| Operative Time (hours), mean (SD)** | 259.1 (130.8) | 1.16 (1.06 - 1.27) | 0.002 |
| Surgical Approach | |||
| Minimally Invasive | 12 (0.6) | 1.00 (REF) | - |
| Open/Other | 88 (1.8) | 2.42 (1.44 - 4.06) | < 0.001 |
| Liver Texture | |||
| Normal/Not documented | 47 (0.9) | 1.00 (REF) | - |
| Cirrhotic/Congested/Fatty/Fibrotic | 53 (3.1) | 2.18 (1.40 - 3.39) | < 0.001 |
| Pringle Maneuver | 29 (2.3) | 1.35 (0.75 - 2.41) | 0.315 |
| Surgical Drain | 56 (2.0) | 1.21 (0.78 - 1.88) | 0.401 |
*
OR reported for each additional 10 years
**
OR reported for each additional hour
Abbreviations: PHLF, post-hepatectomy liver failure; SD, standard deviation; ASA, American Society of Anesthesiologists Classification; SGOT, aspartate transaminase; MIS, minimally invasive surgery