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. 2021 Aug 19;13(9):e13490. doi: 10.15252/emmm.202013490

Figure 2. Comparison of oxygenation and lipid content of target tissues between healthy and obese mice using MSOT imaging.

Figure 2

  1. Reconstructed MSOT image (800 nm) with linear unmixing data of Hb, HbO2 and lipid from chow‐ and HFD‐fed mice. The colour bar shows the colour coding of MSOT a.u. from 0 to maximum (bottom to top) (maximum value chow/HFD: Hb: 1.3/0.6; HbO2: 1.8/0.9; lipid: 27000/27000). Scale bar: 4 mm.
  2. Body weight of chow‐ and HFD‐fed mice. Data represent the mean (± 95% confidence) from 8 animals (n = 8). The unpaired t‐test was used to verify the statistical significance. P = 0.0005.
  3. Unmixing result of Hb, HbO2 and lipid from liver, kidney, iBAT and rpWAT. Each dot represents data from one animal, in total 8 animals (n = 8). Data represent the mean (± 95% confidence). The unpaired t‐test was used to verify the statistical significance. Lipid chow versus HFD liver: P = 0.3339; iBAT: P = 0.0068.
  4. Tissue oxygenation (sO2) and total blood volume (TBV) results from liver, kidney, iBAT and rpWAT. Each dot represents data from one animal, in total 8 animals (n = 8). Data represent the mean (± 95% confidence). The unpaired t‐test was used to verify the statistical significance.

Data information: In the figure, A.U. = arbitrary units.