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. 2021 Aug 2;13(9):e14365. doi: 10.15252/emmm.202114365

Figure 1. ACM patients show high plasma oxLDL, cardiac lipid peroxidation, and oxLDL receptor levels.

Figure 1

  1. oxLDL plasma concentration in ACM patients and HC (n = 36; Mann–Whitney test).
  2. oxLDL plasma concentration in mutated ACM (n = 7) and non‐ACM relatives, carriers of the same causative mutation (n = 9; Mann–Whitney test).
  3. oxLDL plasma concentration in ACM patients carriers of a PKP2 mutation and ACM patients carriers of other desmosomal or non desmosomal mutations, or gene elusive (n = 10 vs. n = 26; one‐way ANOVA).
  4. Representative images of MDA immunostaining (green) on ACM and HC ventricular tissue sections and relative quantification (n = 4 biological replicates; two‐tailed Student’s t‐test). Nuclei are counterstained with Hoechst33342 (blue).
  5. Representative images of CD36 immunostaining (green) on ACM and HC ventricular tissue sections and relative quantification (n = 4 biological replicates; two‐tailed Student’s t‐test). Nuclei are counterstained with Hoechst33342 (blue).

Data information: mean ± SEM. *P < 0.05; **P < 0.01; and ***P < 0.001.

Source data are available online for this figure.