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. 2021 Aug;9(16):1300. doi: 10.21037/atm-21-3746

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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A-CM up-regulated the expression of ATF4 (A), BCL2 (B), and MCL1 (C) mRNA in MCF-7 and MDA-MB-231 cells. Expression level of ATF4, BCL2, and MCL1 mRNA, after MDA-MB-231 cells were co-cultured with A-CM or U-CM for 24 h. (* indicates P<0.05; NC: means natural control group, which were treated with free DMEM/F12). ADSCs, adipose-derived stem cells; UMSCs, umbilical mesenchymal stem cells; A-CM, ADSCs-related medium; U-CM, UMSCs-related medium; ATF4, activating transcription factor 4; DMEM, Dulbecco’s modified Eagle’s medium.