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. 2021 Aug;9(16):1348. doi: 10.21037/atm-21-4174

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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circRHBG upregulation in PCOS. (A) Circular RNA (circRNA) chip detects the differential expression of PCOS-related circRNA in PCOS patients and non-PCOS controls. (B) Volcano plot using fold change >1 and P<0.05 to screen for the differential expression of circRNA. (C) Five upregulated circRNAs were verified by qRT-PCR in 9 pairs of PCOS patients’ and non-PCOS women’s granular cells. PCOS, polycystic ovary syndrome.