Table 2.
Total body bone area as measured by DXA.
| Group | Area (cm2) At Baseline |
Area (cm2) Following HLU |
Area (% Change) Following HLU |
Area (cm2) Sacrifice |
Area (% Change) At Sacrifice |
|
|---|---|---|---|---|---|---|
| Intact Control | (a) | 54.0 ± 1.2 | N/A | N/A | 58.4 ± 0.8 | 8%c*,e |
| OVX | (b) | 54.6 ± 1.0 | N/A | N/A | 59.4 ± 1.5 | 9%c*,e*,i |
| OVX+E2 | (c) | 53.2 ± 1.0 | N/A | N/A | 51.8 ± 0.8 | −2%a*,b*,d*,f*,h |
| OVX+HLU | (d) | 54.3 ± 1.0 | ----See Values for Sacrifice---- | 58.8 ± 1.0 | 8%c*,e | |
| OVX+E2+HLU | (e) | 53.8 ± 0.8 | ----See Values for Sacrifice---- | 53.7 ± 1.4 | 0%a,b*,d,f* | |
| OVX+HLU+REAMB | (f) | 53.8 ± 0.8 | 58.0 ± 1.3 | 8% | 59.1 ± 1.2 | 10%c*,e*,i |
| OVX+E2+HLU+REAMB | (g) | 53.5 ± 0.4 | 54.4 ± 1.3 | 2% | 54.6 ± 1.0 | 0% |
| OVX+HLU+REAMB+EX | (h) | 55.8 ± 0.9 | 56.4 ± 0.7 | 1% | 59.5 ± 1.3 | 6%c |
| OVX+E2+HLU+REAMB+EX | (i) | 54.5 ± 0.9 | 53.8 ± 1.4 | −1% | 55.2 ± 1.2 | 1%b,f |
Values are Means ± SEM of 4-12/group. Letters a-i indicate differences from respectively labeled groups at p ≤ 0.05 or *p ≤ 0.01 (a = vs. Intact controls, b = vs. OVX, c = vs. OVX+E2, d = vs. OVX+HLU, e = vs. OVX+E2+HLU, f = vs. OVX+HLU+REAMB, g = vs. OVX+E2+HLU+REAMB, h = vs. OVX+HLU+REAMB+EX, i = vs. OVX+E2+HLU+REAMB+EX).