Table 5.
Group | Trabecular BMC (mg/mm) |
Trabecular Bone Area (mm2) |
Trabecular BMD (mg/cm3) |
|
---|---|---|---|---|
Intact Control | (a) | 3.2 ± 0.2b*,c*,d*,e,f*,h*,i* | 6.2 ± 0.1c*,e,h | 516 ± 22b*c*,d*,f*,h*,i* |
OVX | (b) | 2.2 ± 0.1a*,d*,f*,h* | 6.5 ± 0.3c | 333 ± 15a*,d*,f*,h* |
OVX+E2 | (c) | 1.9 ± 0.3a*,d*,h* | 5.6 ± 0.2a*,b,d,g*,h* | 333 ± 45a*,d*,f*,h* |
OVX+HLU | (d) | 1.0 ± 0.1a*,b*,c*,e*,g*,h*,i | 6.2 ± 0.1c,e | 160 ± 9a*,b*,c*,e*,g*,h* |
OVX+E2+HLU | (e) | 2.4 ± 0.3a,d*,f,h* | 5.6 ± 0.2a,d,g,h* | 428 ± 53b,d*,f,h* |
OVX+HLU+REAMB | (f) | 1.2 ± 0.1a*,b*,e,g*,h* | 6.2 ± 0.2h | 185 ± 17a*,b*,c*,e,g*,h* |
OVX+E2+HLU+REAMB | (g) | 2.7 ± 0.3d*,f*,h* | 6.7 ± 0.3c*,e | 407 ± 55d*,f*,h* |
OVX+HLU+REAMB+EX | (h) | 0.3 ± 0.1a*,b*,c*,d*,e*,f*g*,i* | 6.9 ± 0.2a,c*,e*,f | 44 ± 10a*,b*,c*,d*,e*,f*,g*,i* |
OVX+E2+HLU+REAMB+EX | (i) | 1.9 ± 0.3a*,d,h* | 6.3 ± 0.3 | 313 ± 48a*,h* |
Values are Means ± SEM of n = 6-12/group. Letters a-f indicate differences from respectively labeled groups at p ≤ 0.05 or *p ≤ 0.01 (a = vs. Intact controls, b = vs. OVX, c = vs.OVX+E2, d = vs. OVX+HLU, e = vs. OVX+E2+HLU, f = OVX+HLU+REAMB, g = OVX+E2+HLU+REAMB), h = vs. OVX+HLU+REAMB+EX, i = vs. OVX+E2+HLU+REAMB+EX. BMC = Bone mineral content, BMD = bone mineral density.