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. 2021 Aug 20;22(5):1197. doi: 10.3892/etm.2021.10631

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of Astragaloside IV on NADPH oxidase in the aortae of diabetic mice. (A) Western blot analysis of various NADPH oxidase subunits, including p22phox, p47phox, p67phox, NOX2, NOX4 and Rac-1. (B) p22phox, (C) p47phox, (D) p67phox, (E) NOX2, (F) NOX4 and (G) Rac-1 levels were then statistically analyzed. Data are presented as the mean ± SEM (n=4-6). ^*P<0.05, ^**P<0.01 and ^***P<0.001 vs. the control group. ^#P<0.05, ^##P<0.01 and ^###P<0.001 vs. the DM group. AS-IV, Astragaloside IV; DM, diabetes mellitus; p22phox, human neutrophil cytochrome b light chain; p47phox, neutrophil cytosolic factor 1; p67phox, neutrophil cytosolic factor 2; NOX, NADPH oxidase.