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Proposed molecular model of AS-IV improving oxidative stress during endothelial dysfunction. AS-IV, Astragaloside IV; NOX, NADPH oxidase; p22phox, human neutrophil cytochrome b light chain; p47phox, neutrophil cytosolic factor 1; p67phox, neutrophil cytosolic factor 2; eNOS, endothelial nitric oxide synthase; p, phosphorylated; NO, nitric oxide; ROS, reactive oxygen species.
