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. 2021 Sep 6;8(1):e000932. doi: 10.1136/bmjresp-2021-000932

Table 2.

Work Ability Score, sick leave, respiratory symptom score and % of predicted FEV1, FVC and FEV1/FVC-ratio prebronchodilator and postbronchodilator by possible confounders: sex, smoking status, highest completed education and age category

Outcome, summary statistics Number Sex Smoking status Highest completed education Age category
Male Female P value Never smoker Former smoker Daily smoker P value Elementary Upper secondary University P value 18–30 31–40 41–52 P value
Work Ability Score <8, n/n total in group (%) 261/1295
(20%)
85/508
(17%)
176/787
(22%)
0.016 112/697
(16%)
78/328
(24%)
71/270
(27%)
<0.001 52/168
(31%)
130/525
(25%)
79/602
(13%)
<0.001 26/212
(12%)
66/310
(21%)
169/773
(22%)
0.007
Sick-leave in the last 12 months, n/n total in group (%) 413/1143
(36%)
113/453
(25%)
300/690
(43%)
<0.001 182/610
(30%)
125/297
(42%)
106/236
(45%)
<0.001 44/116
(38%)
180/464
(39%)
189/563
(34%)
0.203 47/156
(30%)
108/237
(46%)
258/714
(36%)
0.148
Sick leave >14 days, n/n total in group (%) 199/1143
(17%)
43/453
(9%)
156/690
(23%)
<0.001 78/610
(13%)
63/297
(21%)
58/236
(25%)
<0.001 20/116
(17%)
88/464
(19%)
91/563
(16%)
0.428 15/156
(10%)
57/237
(24%)
127/714
(18%)
0.060
Symptom score ≥3, n/n total in group (%) 403/1317
(31%)
120/515
(23%)
283/802
(35%)
<0.001 194/706
(27%)
107/335
(32%)
102/276
(37%)
0.012 50/171
(29%)
177/541
(33%)
176/605
(29%)
0.379 63/216
(29%)
96/314
(31%)
244/787
(31%)
0.874
Symptom score, n, mean (SEM) 1317 515
1.87
(0.11)
802
2.58
(0.10)
<0.001 706
2.10
(0.10)
335
2.37
(0.15)
276
2.72
(0.18)
0.004 171
2.26
(0.21)
541
2.49
(0.12)
605
2.14
(0.11)
0.095 216
2.26
(0.18)
314
2.26
(0.15)
787
2.33
(0.10)
0.911
Pre-FEV1 % of predicted value, n, mean (SEM) 1257 489
94.26
(0.67)
768
96.00
(0.49)
0.033 671
95.44
(0.52)
322
96.57
(0.77)
264
93.50
(0.99)
0.031 158
93.12
(1.08)
515
94.06
(0.63)
584
97.02
(0.58)
<0.001 199
94.45 (0.83)
296
96.11
(0.81)
762
95.25
(0.54)
0.428
Pre-FVC % of predicted value n, mean (SEM) 1257 489
98.25
(0.44)
768
98.25
(0.56)
0.028 671
98.86
(0.46)
322
100.14
(0.68)
264
98.93
(0.82)
0.284 158
97.37
(0.99)
515
98.34
(0.54)
584
100.46
(0.50)
0.002 199
99.25
(0.81)
296
99.91
(0.66)
762
98.92
(0.47)
0.498
Pre-FEV1/FVC-ratio in %, n, mean (SEM) 1257 489
0.79
(0.002)
768
0.77
(0.003)
<0.001 671
0.79
(0.002)
322
0.77
(0.003)
264
0.76
(0.005)
<0.001 158
0.79
(0.006)
515
0.77
(0.003)
584
0.78
(0.003)
0.093 199
0.81
(0.005)
296
0.79
(0.004)
762
0.77
(0.002)
<0.001
Post-FEV1 % of predicted value, n, mean (SEM) 1091 425
96.79
(0.67)
666
99.16
(0.50)
0.004 588
98.22
(0.53)
279
99.88
(0.76)
224
96.25
(1.00)
0.009 131
95.97
(1.16)
442
97.10
(0.64)
518
99.78
(0.57)
<0.001 177
97.99
(0.84)
264
99.10
(0.78)
650
97.95
(0.55)
0.478
Post-FVC % of predicted value, n, mean (SEM) 1091 425
98.57
(0.58)
666
99.88
(0.46)
0.077 588
98.78
(0.49)
279
100.67
(0.70)
224
99.28
(0.80)
0.093 131
97.21
(1.12)
442
98.85
(0.56)
518
100.36
(0.51)
0.012 177
98.92
(0.85)
264
100.03
(0.69)
650
99.23
(0.48)
0.559
Post-FEV1/FVC ratio in %, n, mean (SEM) 1091 425
0.78
(0.004)
666
0.81
(0.002)
<0.001 588
0.81
(0.003)
279
0.80
(0.003)
224
0.78
(0.005)
<0.001 131
0.81
(0.006)
442
0.80
(0.003)
518
0.81
(0.003)
0.029 177
0.85
(0.005)
264
0.81
(0.004)
650
0.79
(0.003)
<0.001

P values were calculated using Fisher’s exact, Pearson χ2 or one-way ANOVA. Statistically significant findings, p<0.05, are bolded

ANOVA, Analysis of variance; FEV, forced expiratory volume; FEV1, forced expiratory volume after 1 s; FVC, forced vital capacity.