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. 2021 Sep 6;11(9):e050259. doi: 10.1136/bmjopen-2021-050259

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Study flowchart for each site. A total of 20 or 30 participants will be recruited through the social network of each site. After 10 participants have been recruited to constitute one wave, they will be randomly allocated into two arms: intervention (Indo-DARPP+TAU) and control (TAU only), with five participants in each arm. Recruitment will be continued until another 10 or 20 participants (second or third wave) join, in a similar procedure. Treatment period will be 12 weeks. Assessments will be conducted four times: T1 (week 0) during baseline or before randomisation, T2 (weeks 13–16) during postassessment or 1–4 weeks after treatment period ends, T3 (week 24) at 3 months after treatment ends and T4 (week 60) at 12 months after treatment ends. DARPP, Drug Addiction Relapse Prevention Programme; TAU, treatment as usual.