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. 2021 Sep 7;21:472. doi: 10.1186/s12935-021-02152-y

Table 4.

Association between CD9 expression and clinicopathological characteristics in cancer patients

Characteristic Number of studies Number of patients Pooled OR (95% CI) p value Heterogeneity
I2 (%) p value Model
Age (old vs young) 10 2500 1.04 (0.88–1.22) 0.670 23.0 0.232 Fixed
Sex (male vs female) 9 1119 0.76 (0.59–0.99) 0.044 0.0 0.815 Fixed
Tumor size (large vs small) 3 1570 0.83 (0.44–1.55) 0.554 68.5 0.042 Random
Tumor grade (high vs low) 6 2340 0.50 (0.16–1.60) 0.244 94.9  < 0.001 Random
Tumor stage (high vs low) 8 2524 0.56 (0.27–1.16) 0.120 89.5  < 0.001 Random
Lymph node metastasis (present vs absent) 8 2312 0.68 (0.41–1.13) 0.137 83.0  < 0.001 Random
Overall stage (high vs low) 7 930 0.45 (0.29–0.72) 0.001 57.6 0.028 Random

CI confidence interval, OR odds ratio