Table 2.
Antifungal susceptibility of malbranchea-like strains studied
| Taxon | Strain | MIC/MEC (μg/mL) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| AMB | FLC | VRC | ITC | PSC | AFG | CFG | MFG | TRB | 5-FC | ||
| Arachnomyces bostrychodes | FMR 17685 | > 16 | > 16 | 2 | > 16 | > 16 | 0.03 | 0.06 | 0.06 | 0.5 | > 16 |
| Currahmyces sparsispora | FMR 17683 | > 16 | > 16 | 4 | > 16 | 2 | > 16 | 8 | > 16 | ≤0.03 | > 16 |
| Malbranchea albolutea | FMR 17679 | 8 | > 16 | 1 | 1 | 0.25 | 0.03 | 0.06 | 0.06 | 0.25 | > 16 |
| FMR 17689 | 8 | > 16 | 2 | > 16 | 1 | 0.12 | 0.06 | 0.25 | 0.25 | > 16 | |
| M. aurantiaca | FMR 17682 | > 16 | > 16 | 1 | > 16 | 0.25 | 0.12 | 1 | 0.12 | 4 | > 16 |
| FMR 17688 | > 16 | > 16 | 2 | > 16 | 0.5 | 0.5 | 0.06 | 1 | 2 | > 16 | |
| M. conjugata | FMR 17697 | 8 | > 16 | 0.5 | 0.25 | ≤0.03 | 0.06 | 0.25 | 0.25 | 1 | > 16 |
| FMR 17699 | > 16 | > 16 | 0.5 | 2 | 0.5 | 0.12 | 0.25 | 0.25 | 1 | > 16 | |
| M. flocciformis | FMR 17698 | > 16 | > 16 | 1 | > 16 | 0.5 | 0.12 | 0.03 | 0.12 | 0,5 | > 16 |
| M. gymnoascoidea | FMR 17681 | > 16 | > 16 | 8 | > 16 | 1 | 0.03 | 0.03 | 0.12 | 0,5 | > 16 |
| M. multiseptata | FMR 17695 | 16 | > 16 | 0.12 | 0.5 | 0.25 | 0.03 | 0.5 | 2 | 1 | > 16 |
| M. stricta | FMR 17680 | 8 | > 16 | 0.25 | 0.12 | 0.12 | 0.03 | 0.25 | 0.25 | 0,12 | > 16 |
| M. umbrina | FMR 17693 | 4 | > 16 | 2 | > 16 | 0.5 | 0.06 | 0.06 | 0.12 | 0.25 | > 16 |
| FMR 17694 | > 16 | > 16 | 4 | > 16 | 0.5 | 0.06 | 1 | 0.12 | 0.25 | > 16 | |
| FMR 17700 | > 16 | > 16 | > 16 | > 16 | > 16 | 0.5 | 1 | 0.5 | > 16 | > 16 | |
| FMR 17701 | > 16 | > 16 | 4 | > 16 | 0.12 | 0.03 | 0.03 | 0.03 | 0.12 | > 16 | |
| M. zuffiana | FMR 17690 | > 16 | > 16 | 1 | > 16 | 0.5 | 0.05 | 1 | 4 | 0.25 | > 16 |
| Pseudomalbranchea gemmata | FMR 17684 | 2 | > 16 | 0.25 | 0.25 | 0.25 | 16 | 1 | 16 | ≤0.03 | > 16 |
| Spiromastigoides geomycoides | FMR 17686 | > 16 | > 16 | 2 | 1 | 1 | > 16 | 2 | > 16 | 0.12 | > 16 |
| FMR 17696 | > 16 | > 16 | 2 | 0.5 | 0.5 | 2 | 16 | > 16 | 0.06 | > 16 | |
AMB amphotericin B, FLC fluconazole, VRC voriconazole, ITC itraconazole, PSC posaconazole, AFG anidulafungin, CFG caspofungin, MFG micafungin, TRB terbinafine, 5-FC 5-fluorocytosine, ND Non-determined due to no fungal growth under the conditions stablished by the CLSI protocol