Table 4.
Analysis of Factors Predicting OS.
| Items | Cox's proportional hazard regression model | |||
|---|---|---|---|---|
| P value | HR | 95% CI | ||
| Lower | Higher | |||
| Univariate Cox's regression | ||||
| Circ-SMARCA5 expression (high vs low) | .025 | 3.788 | 1.178 | 12.179 |
| MiR-432 expression (high vs low) | .021 | 0.225 | 0.063 | 0.801 |
| Age (≥60 years vs <60 years) | .225 | 2.191 | 0.617 | 7.779 |
| Gender (male vs female) | .531 | 1.611 | 0.363 | 7.151 |
| Multiplicity (multiple vs single) | .016 | 3.565 | 1.263 | 10.067 |
| Tumor size (≥3.0 cm vs <3.0 cm) | .024 | 3.220 | 1.165 | 8.898 |
| Tumor stage (T2-T4 vs Ta&T1) | .006 | 4.547 | 1.551 | 13.336 |
| LYN metastasis (yes vs no) | .009 | 4.742 | 1.480 | 15.190 |
| Pathological grade (high vs low) | .029 | 3.593 | 1.141 | 11.315 |
| Forward stepwise multivariate Cox's regression | ||||
| Circ-SMARCA5 expression (high vs low) | .044 | 3.370 | 1.035 | 10.986 |
| Tumor stage (T2-T4 vs Ta&T1) | .010 | 4.126 | 1.396 | 12.192 |
Factors affecting OS were analyzed by the univariate and forward stepwise multivariate Cox's proportional hazard regression model.
Abbreviations: OS, overall survival; HR, hazard ratio; CI, confidence interval; circ-SMARCA5, circular RNA SMARCA5; miR-432, microRNA-432; LYN, lymph node.