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. 2021 Sep 3;70(35):1183–1190. doi: 10.15585/mmwr.mm7035a1

TABLE 2. Estimated vaccination coverage with selected vaccines and doses among adolescents aged 13–17* years, by metropolitan statistical area† and by poverty level — National Immunization Survey–Teen, United States, 2020.

Vaccine MSA, % (95% CI)§
Below poverty level, % (95% CI)§
At or above poverty level, % (95% CI)§
Non-MSA
MSA nonprincipal city
MSA principal city
Non-MSA
MSA nonprincipal city
MSA principal city
Non-MSA
MSA nonprincipal city
MSA principal city
(n = 3,678) (n = 8,409) (n = 8,076) (n = 631) (n = 865) (n = 1,352) (n = 2,938) (n = 7,246) (n = 6,420)
Tdap ≥1 dose
90.7 (88.7–92.3)
90.6 (89.3–91.8)
89.3 (87.7–90.7)
93.1 (89.7–95.5)
89.0 (84.7–92.1)
89.6 (86.3–92.2)
89.8 (87.4–91.9)
91.1 (89.7–92.3)
89.2 (87.3–90.9)
MenACWY**
≥1 dose
85.7 (83.7–87.5)††
89.4 (87.9–90.7)
90.2 (88.7–91.5)
86.1 (81.8–89.5)††
87.2 (82.6–90.6)
91.6 (88.8–93.7)
85.6 (83.2–87.7)††
90.2 (88.6–91.5)
89.4 (87.5–91.0)
≥2 doses§§
50.1 (43.4–56.9)
58.5 (54.0–62.8)††
50.6 (45.2–56.1)
47.4 (33.5–61.7)
47.6 (33.0–62.7)
48.6 (35.8–61.7)
50.2 (42.3–58.0)
61.2 (56.6–65.6)††
50.2 (44.1–56.4)
HPV¶¶ vaccine
All adolescents
≥1 dose
68.0 (65.3–70.6)††
74.2 (72.5–75.9)††
77.8 (75.8–79.6)
73.6 (67.8–78.7)††
83.6 (79.5–87.0)
85.7 (82.0–88.7)
64.9 (61.7–67.9)††
73.1 (71.3–74.9)††
76.2 (74.0–78.3)
HPV UTD***
49.2 (46.3–52.1)††
59.1 (57.2–61.0)
60.4 (58.2–62.6)
56.7 (50.3–62.9)
63.8 (58.1–69.2)
64.4 (59.2–69.3)
46.0 (42.9–49.3)††
58.4 (56.4–60.4)
59.8 (57.4–62.2)
Females
≥1 dose
67.8 (63.7–71.7)
††
76.7 (74.5–78.8)
79.8 (76.9–82.4)
75.2 (66.4–82.2)††
84.4 (78.9–88.6)
87.2 (82.0–91.0)
63.6 (58.6–68.2)††
75.7 (73.3–78.0)
78.8 (75.7–81.7)
HPV UTD
50.3 (46.0–54.6)††
62.2 (59.6–64.7)
63.2 (59.9–66.4)
56.9 (47.6–65.8)
65.3 (56.8–72.9)
66.0 (58.2–73.0)
46.8 (42.0–51.6)††
61.9 (59.1–64.5)
63.5 (60.0–67.0)
Males
≥1 dose
68.1 (64.6–71.5)††
71.9 (69.3–74.4)††
75.8 (73.2–78.3)
71.6 (63.7–78.4)††
82.9 (76.5–87.8)
84.3 (78.8–88.6)
66.1 (61.9–70.0)††
70.7 (68.0–73.3)
73.7 (70.5–76.6)
HPV UTD
48.1 (44.3–52.0)††
56.2 (53.4–58.9)
57.8 (54.8–60.7)
56.4 (47.8–64.7)
62.5 (54.5–69.8)
62.9 (55.8–69.4)
45.4 (41.2–49.7)††
55.2 (52.2–58.1)
56.2 (52.8–59.5)
MMR ≥2 doses
92.8 (91.0–94.2)
92.4 (91.2–93.5)
92.3 (90.9–93.5)
93.6 (89.4–96.2)
89.5 (83.8–93.3)
90.8 (86.2–94.0)
92.3 (90.2–94.0)
92.9 (91.6–93.9)
92.4 (90.9–93.6)
Hepatitis A vaccine ≥2 doses†††
76.2 (73.7–78.5)††
82.0 (80.6–83.4)
83.6 (81.9–85.2)
80.4 (75.0–84.9)
82.1 (77.1–86.3)
83.0 (78.1–87.0)
74.4 (71.5–77.0)††
81.8 (80.2–83.3)
83.6 (81.7–85.3)
Hepatitis B vaccine ≥3 doses
92.4 (90.6–93.9)
92.9 (91.7–93.9)
92.3 (90.9–93.5)
92.8 (89.0–95.4)
91.0 (86.3–94.2)
89.9 (85.5–93.2)
92.0 (89.8–93.8)
93.1 (91.9–94.1)
92.9 (91.5–94.1)
Varicella
History of varicella§§§
10.1 (8.6–11.8)
8.2 (7.2–9.4)
8.0 (6.9–9.4)
9.8 (6.9–13.6)
13.3 (9.4–18.5)
9.3 (6.4–13.3)
10.3 (8.6–12.3)††
7.2 (6.2–8.4)
7.8 (6.5–9.3)
No history of varicella disease
≥1 dose vaccine
96.1 (94.6–97.1)
95.8 (94.8–96.6)
95.3 (94.1–96.2)
95.9 (91.9–97.9)
96.9 (94.6–98.2)
94.0 (90.0–96.4)
96.1 (94.4–97.3)
95.5 (94.3–96.4)
95.5 (94.2–96.5)
≥2 doses vaccine
92.5 (90.7–94.0)
92.0 (90.6–93.2)
91.6 (90.1–92.9)
94.2 (90.1–96.6)
87.9 (81.2–92.4)
90.7 (85.7–94.0)
91.7 (89.4–93.5)
92.4 (91.0–93.5)
91.6 (90.0–93.0)
History of varicella or received ≥2 doses VAR 93.2 (91.6–94.6) 92.7 (91.4–93.8) 92.3 (90.9–93.5) 94.7 (91.0–97.0) 89.5 (83.6–93.4) 91.5 (87.0–94.6) 92.5 (90.5–94.1) 92.9 (91.6–94.0) 92.2 (90.7–93.5)

Abbreviations: CI = confidence interval; HPV = human papillomavirus; MenACWY = quadrivalent meningococcal conjugate vaccine; MMR = measles, mumps, and rubella vaccine; MSA = metropolitan statistical area; NIS-Teen = National Immunization Survey–Teen; Tdap = tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine; UTD = up to date; VAR = varicella vaccine.

* Adolescents (20,163) in the 2020 NIS-Teen were born during January 2002–January 2008.

MSA status was determined based on household-reported county of residence and was grouped into three categories: MSA principal city, MSA nonprincipal city, and non-MSA. MSA and principal city were as defined by the U.S. Census Bureau https://www.census.gov/programs-surveys/metro-micro.html). Non-MSA areas include urban populations not located within an MSA as well as completely rural areas.

§ Estimates with 95% CI widths >20 might not be reliable.

Includes percentages receiving Tdap vaccine at age ≥10 years.

** Includes percentages receiving MenACWY and meningococcal-unknown type vaccine.

†† Statistically significant difference (p<0.05) in estimated vaccination coverage by metropolitan statistical area; referent group was adolescents living in MSA principal city areas.

§§ ≥2 doses of MenACWY or meningococcal-unknown type vaccine. Calculated only among adolescents who were aged 17 years at interview. Does not include adolescents who received 1 dose of MenACWY vaccine at age ≥16 years.

¶¶ HPV vaccine, nine-valent (9vHPV), quadrivalent (4vHPV), or bivalent (2vHPV) in females and males combined.

*** HPV UTD includes those with ≥3 doses, and those with 2 doses when the first HPV vaccine dose was initiated before age 15 years and there was at least 5 months minus 4 days between the first and second dose. This update to the HPV recommendation occurred in December 2016.

††† In July 2020, ACIP revised recommendations for HepA vaccination to include catch-up vaccination for children and adolescents aged 2–18 years who have not previously received HepA vaccine at any age. https://www.cdc.gov/mmwr/volumes/69/rr/rr6905a1.htm?s_cid=rr6905a1

§§§ By parent or guardian report or provider records.