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. Author manuscript; available in PMC: 2021 Sep 7.
Published in final edited form as: Contemp Clin Trials. 2021 Mar 24;104:106367. doi: 10.1016/j.cct.2021.106367

Table 4.

Statin myalgia clinical index score (SMCI) [46]

Regional distribution/pattern POINTS
Clinical symptoms (new or increased unexplained muscle symptoms)
Symmetric hip flexors/thigh aches 3
Symmetric calf aches 2
Symmetric upper proximal aches 2
Non-specific asymmetric, intermittent 1
Temporal pattern
Symptoms onset <4 weeks 3
Symptoms onset 4–12 weeks 2
Symptoms onset >12 weeks 1
Dechallenge
Improves upon withdrawal (<2 wks) 2
Improves upon withdrawal (2–4 wks) 1
Does not improve upon withdrawal 0
Rechallenge
Symptoms reoccur upon rechallenge < 4 wks 3
Symptoms reoccur upon rechallenge 4–12 wks 1
Statin myalgia clinical index score
Probable 9–11
Possible 7–8
Unlikely <7