. Author manuscript; available in PMC: 2021 Sep 7.

Published in final edited form as: Circ Cardiovasc Imaging. 2020 Feb 17;13(2):e009829. doi: 10.1161/CIRCIMAGING.119.009829

Table 3:

Multivariable Cox analysis of EAT volume and attenuation for hard events (Myocardial infarction and cardiac death).

Model 1 - with EAT volume	Hazard Ratio (95% CI)	P-value
ASCVD risk score	1.04 (1.02–1.07)	<0.001^†
CAC score (AU) ^*	1.21 (1.12–1.30)	<0.001^†
EAT volume (cm³) ^*	1.49 (1.00–2.21)	0.046^†
Model 2 - with EAT attenuation	Hazard Ratio (95% CI)	P-value
ASCVD risk score	1.05 (1.03–1.07)	<0.001^†
CAC score (AU)	1.22 (1.13–1.30)	<0.001^†
EAT attenuation (HU) ^*	0.79 (0.63–1.01)	0.057
Model 3 - with EAT volume	Hazard Ratio (95% CI)	P-value
Waist circumference (cm)	0.96 (0.86–1.04)	0.314
BMI (kg/m²)	1.01 (0.93–1.10)	0.851
EAT volume (cm³)	2.97 (1.70–5.21)	<0.001^†
Model 4 - with EAT attenuation	Hazard Ratio (95% CI)	P-value
Waist circumference (cm)	0.99 (0.91–1.08)	0.792^†
BMI (kg/m²)	1.02 (0.94–1.10)	0.675^†
EAT attenuation (HU)	0.65 (0.49–0.87)	0.004^†

CAC score (AU) and EAT volume (cm³) two-fold increase/doubling. EAT attenuation per-5 HU increase.

^†

P-values <0.05 are statistically significant.

Abbreviations: ASCVD: atherosclerotic cardiovascular disease, BMI: body mass index, CAC: coronary artery calcium, CI: confidence interval, EAT: epicardial adipose tissue