Table 1.

Summary of Models Investigating Associations With Conversion to Amyloid Positivity

	Independent Variable
	Age	APOE ε4+	Education	Length of Follow-up	ADNI_MEM	PACC	CSF p-Tau+	CSF Aβ	CSF p-Tau
Logistic Regression Models	NS	↑	↑	↑
	NS	↑	↑	↑	↑
	NS	↑	↑	↑		↑
	NS	↑	↑	↑	↑		NS
	NS	↑	↑	↑		↑	NS
	NS	NS	↑	↑	↑			↓	↑
	NS	NS	↑	↑		NS		↓	↑
Cox Proportional Hazards Models	NS	↑	↑		↑
	NS	↑	↑			↑
	NS	NS	NS	NS				↓	↑
	NS	NS	NS			↑		↓	↑

Each row corresponds to a separate model. Arrows indicate the directions of the statistically significant associations of the independent variables with amyloid positivity. Cells are left blank for variables not included in the models. We indicate CSF Aβ level in this table, whereas the results reported in Elman et al. (4) are based on CSF Aβ abnormality, which is given by negating CSF Aβ level.

Aβ, amyloid-β; ADNI_MEM, Alzheimer’s Disease Neuroimaging Initiative memory factor score; CSF, cerebrospinal fluid; NS, not significant; PACC, Preclinical Alzheimer Cognitive Composite; p-tau, phosphorylated tau.