Plot against calendar time of unadjusted breast cancer log10-incidence and adjusted log10-incidence for women at the reference level of risk factors for a 60-64 year-old woman in the U.S. The reference categories are <25.3 for BMI, (13.1, 13.6] for age at menarche, (2.9,3.61] for number of births and (21.6,22.1] for age at first live birth.
Figure 4 contains observed breast cancer incidence on the log-10 scale in 60-64 year old women and breast cancer incidence that would have been observed when risk factors are held fixed at a low-risk reference category. Panels A) through D) correspond to adjustment for BMI, age at menarche, number of live births and age at first live birth, respectively.