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. 2021 Apr-Jun;14(2):160–165. doi: 10.4103/JCAS.JCAS_130_19

Table 3.

Advantages of PRF over PRP

1. The procedure is easy and less time-consuming
2. The procedure is painless as no need to inject the sample
3. Lack of biochemical modification as no anticoagulants are needed
4. The method preparation and application is simple and is cost- effective process
5. Long‑term effect––growth factors are released slowly over a period of 7 or more days
6. Able to support cytokines enmeshment and cellular migration
7. Increased incorporation of the circulating cytokines in the fibrin meshes (intrinsic cytokines)
8. It supports and accelerates the healing process due to slow polymerization
9. Helps in hemostasis
10. Three‑dimensional structure gives elasticity and flexibility to PRF membrane