Extended Data Table 3.
Virus for infection | Hamster ID | FFRNT50s against SARS-CoV-2 spike variants | |||||
---|---|---|---|---|---|---|---|
USA-WA1/2020 mNG | Alpha+E484K-spike mNG | Beta-spike mNG | Gamma-spike mNG | Epsilon-spike mNG | Delta-spike mNG | ||
USA-WA1/2020 | 1 | 4574 | 3509 | 3590 | 4437 | 4843 | 6410 |
2 | 2299 | 2042 | 2094 | 1850 | 2207 | 2337 | |
3 | 953 | 510 | 370 | 807 | 1125 | 1612 | |
4 | 2205 | 1682 | 723 | 1707 | 871 | 1232 | |
Mean | 2508 | 1936 | 1694 | 2200 | 2262 | 2898 | |
Alpha+E484 K-spike | 5 | 718 | 3794 | 2628 | 3627 | 601 | 462 |
6 | 1326 | 5262 | 2624 | 3211 | 1248 | 719 | |
7 | 1237 | 4554 | 2115 | 3225 | 844 | 477 | |
8 | 405 | 4930 | 2181 | 2210 | 372 | 248 | |
Mean | 922 | 4635 | 2387 | 3068 | 766 | 477 | |
Beta-spike | 9 | 1881 | 3305 | 4574 | 3994 | 2047 | 2005 |
10 | 582 | 1852 | 2857 | 2527 | 545 | 584 | |
11 | 1184 | 2374 | 3746 | 3139 | 906 | 988 | |
12 | 920 | 1692 | 1554 | 2068 | 688 | 680 | |
Mean | 1142 | 2306 | 3183 | 2932 | 1047 | 1064 | |
Gamma-spike | 13 | 1391 | 3638 | 7481 | 7345 | 1272 | 1505 |
14 | 2251 | 5095 | 7255 | 7892 | 1282 | 1566 | |
15 | 656 | 1638 | 1274 | 2734 | 203 | 268 | |
16 | 828 | 2521 | 3882 | 3986 | 514 | 633 | |
Mean | 1282 | 3223 | 4973 | 5489 | 818 | 993 | |
Epsilon-spike | 17 | 1982 | 1315 | 2236 | 1548 | 3379 | 2149 |
18 | 2205 | 1991 | 2742 | 3084 | 4212 | 4069 | |
19 | 1928 | 1182 | 1158 | 1326 | 2419 | 2208 | |
20 | 2930 | 4189 | 3004 | 2268 | 4641 | 4016 | |
Mean | 2261 | 2169 | 2285 | 2057 | 3663 | 3111 |