Table 3. Significance of changes in serum concentrations of hydroxyproline (HP), the C-terminal propeptide of procollagen I (CP), and cross-linked telopeptides (XL).
These changes were measured within the ACA group and within the CA group across various time points.
| Marker | Treatment | Test within-subject effects (Greenhouse-Geisser) | Statistical significance of changes between specific time points (weeks) | |||||
|---|---|---|---|---|---|---|---|---|
| 0–2 | 0–4 | 0–8 | 2–4 | 2–8 | 4–8 | |||
| HP | CA | F(2.218, 28.837) = 3.085, p = 0.056 | n.s | n.s | n.s | n.s | n.s | n.s |
| ACA | F(1.840, 36.808) = 4.734, p = 0.017 | n.s | p = 0.009 | n.s | n.s | n.s | p = 0.038 | |
| CP | CA | F(1.436, 20.102) = 3.123, p = 0.08 | n.s | n.s | n.s | n.s | n.s | n.s |
| ACA | F(2.261, 42.966) = 12.439, p < 0.005 | p = 0.039 | p = 0.006 | p = 0.002 | p = 0.01 | n.s | n.s | |
| XL | CA | F(1.546, 13.914) = 1.844, p = 0.198 | n.s | n.s | n.s | n.s | n.s | n.s |
| ACA | F(2.148, 27.929) = 18.669, p < 0.005 | n.s | p = 0.007 | p < 0.005 | n.s | p = 0.007 | n.s | |
n.s, not significant.